|
Symbol Name ID |
Dnmt3a
DNA methyltransferase 3A MGI:1261827 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Neuroendocrine neoplasm |
Optic nerve hypoplasia |
Ventriculomegaly |
Encephalomalacia |
Chiari malformation |
Chiari type I malformation |
Anxiety |
Schizophrenia |
Atypical behavior |
Bipolar affective disorder |
Aggressive behavior |
Intellectual disability |
Intellectual disability, mild |
Intellectual disability, moderate |
Intellectual disability, severe |
Developmental regression |
Global developmental delay |
Seizure |
Febrile seizure (within the age range of 3 months to 6 years) |
| Disease(s) Associated with DNMT3A | |||||||||||||||||||
| Tatton-Brown-Rahman syndrome |
| Mouse Phenotypes | nervous system phenotype |
convulsive seizures |
decreased motor neuron number |
abnormal neuromuscular synapse morphology |
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| Availability | Mouse Genotype | ||||
| Dnmt3atm1b(KOMP)Wtsi/Dnmt3a+ | |||||
| Dnmt3atm1Jae/Dnmt3atm1Jae Tg(Nes-cre)1Atp/0 (conditional) |
* | ||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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